Transdiagnostic Symptom Dimensions in Individuals at Ultra-High Risk for Psychosis: Towards Dimensional Representations of Pluripotent Risk

Abstract

Intro: Research has shifted focus from categorical to dimensional conceptualisations of mental health conditions. This is supported by high overlap between disorders, particularly psychosis spectrum and affective disorders, which cuts across traditional diagnostic boundaries. While there is evidence for a general factor of psychopathology in individuals with schizophrenia, schizoaffective disorder, and psychotic bipolar I disorder, transdiagnostic dimensions of psychopathology have not been investigated in young individuals at ultra-high risk for psychosis, that is, youth with pluripotent symptom patterns preceding first-episode psychosis. The current study sought to investigate (1) whether ..